emka TECHNOLOGIES S.A.
59, bd. Général Martial Valin
75015 Paris - France
tel: + 33 (0)1 40 60 76 00
fax: +33 (0)1 40 60 65 55
e-mail: emka@emka.fr
emka TECHNOLOGIES Inc.
307 Annandale Road, suite 203
Falls Church, VA 22042 - USA
tel: +1 (703) 237-9001
fax: +1 (703) 237-9006
e-mail: emkatech@emkatech.com
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emka TECHNOLOGIES' applications for safety pharmacology and toxicology studies
    what you need

  your applications
  s7a & s7b requirements s7a & s7b requirements
  ecg ecg
  ecg - sedated mice ecg - sedated mice
  cardiovascular cardiovascular
  baroreflex sensitivity baroreflex sensitivity
  thrombosis thrombosis
  working heart working heart
  electrophysiology electrophysiology
  cardiac ap cardiac ap
  cardiac conductivity cardiac conductivity
  pulmonary pulmonary
  cigarette exposure cigarette exposure
  cardiorespiratory cardiorespiratory
  gas mixture exposure gas mixture exposure
  recording apneas recording apneas
  hemodynamics hemodynamics
  pv loops pv loops
  minipigs minipigs
  primates primates
  telemetry telemetry
  telemetry in primates telemetry in primates
  telemetry in rodents telemetry in rodents
  telemetry in dogs telemetry in dogs
  telemetry in swine telemetry in swine
  isolated organs isolated organs
  cns studies cns studies
  behavior behavior
  case studies case studies
  arrange a demo arrange a demo
  request a quote request a quote
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sharp research

emka TECHNOLOGIES provides complete and integrated solutions for researchers performing isolated tissue/organ, cardiovascular, ecg, electrophysiology, pulmonary, telemetry, behaviour studies.

 

Whatever the scale and complexity of your project, contact us to obtain a professional competitively priced solution adapted to your needs.

telemetry
A full customized solution for toxicology and safety pharmacology laboratories wanting to record ecg and other parameters from freely moving subjects.

pulmonary
Full hardware and software plethysmography solutions: whole-body plethysmography with unrestrained freely moving subjects; double-chamber plethsymography with restrained subjects; resistance/compliance measurements with anesthetized subject.

ecg
A range of solutions for performing ecg studies on different animals from mouse to primate. Hardwire, non-invasive and implantable setups available. Powerful analysis from ecgAUTO software.

pv loops
Characterization of the intact heart's performance under various situations (drugs, disease, characterization of mouse strains…) is possible by use of conductance catheters measuring pressure-volume (PV) changes in the left ventricle. Configuration and analysis performed in iox via dedicated PV analyzer.

working heart
Complete setup to run working heart experiments on hearts from mice, rats, guinea pigs or rabbits. In addition to left ventricular pressure (lvp), ecg may be acquired.

isolated organs
emka TECHNOLOGIES provides a complete suite of integrated hardware and software solutions for studying isolated tissue, specifically contractile tissue such as aortic rings, trachea, papillary muscle, uterine tissue, isolated heart, microvessels.

ecg in sedated mice
Hardwire or telemetry setup for acquisition of ecg data from sedated mice. ecg is one of the parameters commonly measured during phenotyping of genetically modified strains.

cardiovascular
Integrated hardware and software solutions for different types of cardiovascular studies: isolated heart (working heart or Langendorff), pressure-volume loops, ecg,…

gas mixture exposure
We supply setups for the study of exposure to different gas mixtures (up to 3 gases). Setup includes mass-flow controllers for controlling gas flow and iox software for remote control and acquisition.

baroreflex sensitivity
Assessment of baroreflex sensitivity is based on analysis of a blood pressure signal. The analysis module is available as an option with the bp analyser.

thrombosis
In the described setup, thrombus formation is induced mechanically and followed by measuring flow downstream.

electrophysiology
Solutions for studying the electrical and, where appropriate, contractile properties of excitable tissues: single-cell or multicellular recording from isolated tissue, non-invasive eeg recordings...

cardiac action potential
Full setups for studying electrical activity of individual cardiac cells, such as Purkinje fibre, bundle of His and papillary muscles.

cardiac conductivity
Full setups for studying conduction pathways in health and disease: specialist catheters and stimulus generators, amplifier, software for acquisition and analysis.

cigarette exposure
For studying acute, sub-chronic and chronic animal models of cigarette-smoking induced lung disease.

cardiorespiratory studies
Record cardiac and respiratory activity simultaneously in conscious rats or mice.

hemodynamics
Setups to study hemodynamics in anesthetized rats and mice.

minipigs
Non-invasive telemetry is ideally suited for for data acquisition in minipigs.

primates
Acquisition and analysis of physiological data from nonhuman primates (nhp) presents a unique set of challenges. emka TECHNOLOGIES provides products to meet this need, including noninvasive or implantable telemetry, video and advanced ecg analysis.

telemetry in rodents
Use of transmitter implants makes it possible to study conscious freely moving small animals, such as mice and rats.

telemetry in dogs
A fully customized solution for recording different parameters from freely moving conscious dogs: ecg (1-, 6- or 7-lead) for up to 3 days, blood pressure, skin temperature, activity, and respiration. Customized clothing.

telemetry in primates
A fully customized solution for recording different parameters from freely moving conscious dogs: ecg (1-, 6- or 7-lead) for up to 3 days, skin temperature, activity, and respiration. Customized clothing.

telemetry in swine
The minipig is a particularly useful species for evaluating cardiovascular and dermatological toxicities and predicting similar drug liabilities in humans.

CNS studies
emka TECHNOLOGIES provides several hardware and software products for the study of the CNS system at different levels (electrophysiological, behavioural,...).

behavior
For studying eating/drinking behaviour or motor co-ordination.



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