For blood flow measurement

An extensive range of flowmeters is available to measure volume flow through arteries, veins and ducts of different species and of diameter 0.25 mm and upwards.

In addition, tubing and perfusion applications are also possible.

All models provide calibrated analog signals (in flow units) that can be directly connected to IOX2 software.

Transit-time ultrasound technology: What is it? 

Ultrasound That Measures Volume Flow, Not Velocity. Using wide-beam illumination, transducers pass ultrasonic signals back and forth, alternately intersecting flowing blood in upstream and downstream directions. The transit time of the ultrasonic beam is decreased when traveling downstream with the blood flow and increased when traveling upstream against the flow. The difference between the integrated transit times is a measure of volume flow.

Perivascular volume blood flow measurements

Transonic’s signature high-resolution ultrasonic transit-time technology can measure volume blood flows of < 1 mL/min in vessels as small as 0.3 mm in diameter as well as flows up to 200 L/min in 36 mm diameter vessels.

Transonic’s flow measurement technology gives precision volume flow measurements in extracorporeal and ex vivo applications such as for Langendorff and isolated organ preparations and pump perfused protocols.

Output Parameters:

  • Cardiac output and cardiovascular dynamics
  • Renal hypertension
  • Carotid thrombosis
  • Stroke models
  • Hemorrhagic shock
  • Ischemia/reperfusion
  • Portal hypertension etc.

 

Tubing: Clamp or In line flow sensors

PXN Inline Flowsensors utilize a scheme of ultrasonic illumination that makes it possible to manufacture a flow-through Sensor with a smooth, cylindrical interior without compromising measurement accuracy. These Flowsensors offer more flexibility over Clamp-on, as measurement doesn’t depend on the type and exact size of tubing on which they are used. Small diameter PXN Inlines are ideal for low flow isolated heart or perfused organ studies.

PXL Clamp-on Tubing Flowsensors clip on the outside of flexible laboratory tubing. No physical contact is made with the fluid media. They have become the standard for OEM medical design and preclinical extracorporeal use by providing non-invasive measurement with high accuracy and stability. Measurements are reliable even in challenging electromagnetic environments.

PXL-Series Flowsensors can be factory calibrated and programmed for up to 4 different fluid, temperature, tubing, and flow rate combinations. Sensor size isdetermined by the outside diameter of the tubing.

Tubing applications include:

  • Extracoporeal shunts and cannulas
  • Fluid phantoms and mock circulatory models
  • Artificial heart and VAD performance
  • Pulse duplication/heart valve studies
  • Isolated perfused organ studies
  • Accurate: Hight resolution and immediate beat to beat flow measurement
  • Repeatable
  • Validated: Gold standard measurement using transit-time ultrasound
  • Modular: flexibility to expand capacity and add modules as needed. Universal BNC analog outputs are compatible with most data acquisition systems.

A typical setup includes:

  • An acquisition computer equipped with IOX2 software
  • An usbACQ device
  • A multi-channel Console:
    • T402 Console holds up to 2 double-bay flow modules, 4 single-bay pressure modules, or a combination of the two sizes.
    • T403 Console holds up to 3 double-bay flow modules, 6 single-bay pressure modules, or a combination of the two sizes.
  • A Module with flow sensors:
    • TS410 Tubing Flowmeter Module, with PXL-Series sterile tubing flow sensors for volume flow measurements in tubing applications.
    • TS420 Perivascular Flowmeter Module, with flow probes for vessels 0.25 mm and larger for absolute blood flow measurements in arteries, veins & ducts for acute & chronic cardiovascular research applications.

Perivascular flowprobes

Precision Tubing Flowsensors

 

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