Transit-time ultrasound technology: What is it?
Ultrasound That Measures Volume Flow, Not Velocity. Using wide-beam illumination, transducers pass ultrasonic signals back and forth, alternately intersecting flowing blood in upstream and downstream directions. The transit time of the ultrasonic beam is decreased when traveling downstream with the blood flow and increased when traveling upstream against the flow. The difference between the integrated transit times is a measure of volume flow.
Perivascular volume blood flow measurements
Transonic’s signature high-resolution ultrasonic transit-time technology can measure volume blood flows of < 1 mL/min in vessels as small as 0.3 mm in diameter as well as flows up to 200 L/min in 36 mm diameter vessels.
Transonic’s flow measurement technology gives precision volume flow measurements in extracorporeal and ex vivo applications such as for Langendorff and isolated organ preparations and pump perfused protocols.
Output Parameters:
- Cardiac output and cardiovascular dynamics
- Renal hypertension
- Carotid thrombosis
- Stroke models
- Hemorrhagic shock
- Ischemia/reperfusion
- Portal hypertension etc.
Tubing: Clamp or In line flow sensors
PXN Inline Flowsensors utilize a scheme of ultrasonic illumination that makes it possible to manufacture a flow-through Sensor with a smooth, cylindrical interior without compromising measurement accuracy. These Flowsensors offer more flexibility over Clamp-on, as measurement doesn’t depend on the type and exact size of tubing on which they are used. Small diameter PXN Inlines are ideal for low flow isolated heart or perfused organ studies.
PXL Clamp-on Tubing Flowsensors clip on the outside of flexible laboratory tubing. No physical contact is made with the fluid media. They have become the standard for OEM medical design and preclinical extracorporeal use by providing non-invasive measurement with high accuracy and stability. Measurements are reliable even in challenging electromagnetic environments.
PXL-Series Flowsensors can be factory calibrated and programmed for up to 4 different fluid, temperature, tubing, and flow rate combinations. Sensor size isdetermined by the outside diameter of the tubing.
Tubing applications include:
- Extracoporeal shunts and cannulas
- Fluid phantoms and mock circulatory models
- Artificial heart and VAD performance
- Pulse duplication/heart valve studies
- Isolated perfused organ studies