European Respiratory Society Congress 2025

The 2025 European Respiratory Society Congress will take place in Amsterdam, Netherlands at the RAI Amsterdam Convention Center from September 17th to the October 1st.

Join us at booth G24

In vivo, ex vivo and in vitro Smoke Exposure

The expoCube is an Air Liquid Interface (ALI)/Transwell in vitro / ex vivo exposure system that efficiently deposits aerosols onto cells and tissues. When combined with SCIREQ’s inExpose^® inhalation exposure platform, the expoCube allows researchers to integrate in vitro, ex vivo and in vivo models, optimizing compound usage while adhering to the 3Rs principle.

The expoCube features:

Reproducibility: Efficient, uniform, and precise exposure of particulates onto target cells and tissues.
Precision: Optimized flow paths using advanced computational fluid dynamics (CFD) modelling.
Deposition: Patented thermophoresis, increasing the deposition efficiency of small particles without imparting unnatural electrostatic charges onto the aerosols.

New Research Platform for Precision Cut Lung Slices

Precision-Cut Lung Slices (PCLS) help researchers understand pathophysiological mechanisms associated with various respiratory diseases. The physioLens is a scientific platform that provides accurate physiological and image-based outcomes in a reproducible fashion. It includes an automated microscope and fluid handling system. 

The physioLens features:

Automation: The physioLens is capable of capturing images anywhere on slices in a 6 well plate and apply doses without user intervention. Images are analyzed in real-time to provide bronchoconstriction data.
Dosing: Agonists are provided to the slice without user intervention by a dosing nozzle, that can provide a 95% media exchange in less than 20 seconds. In addition, eight dosing bottles are provided to complete a detailed dose response automatically.
Image analysis: Images of airways are automatically processed to capture the lumen contours and then calculate bronchoconstriction.
Slice Scanning: Navigating a slice is not necessary with our airway configuration wizard complete with full slice mapping. Fine tune the positions of interest with our click-and-drag XY navigation.

in vivo Respiratory Mechanics Measurements

The flexiVent lung function solution is widely regarded as the gold standard for in vivo respiratory mechanics measurements. It goes beyond traditional resistance and compliance mechanics of pulmonary ventilation, and captures crucial details about the mechanical properties of conducting airways, terminal airways and parenchyma.

The flexiVent achieves the highest sensitivity and reproducibility by precisely controlling experimental conditions.

vivoFlow+ plethysmograph

vivoFlow+ plethysmograph allows studying pulmonary function in conscious, spontaneously breathing laboratory subjects.
The standard barometric plethysmography technique measures flow and pressure changes that occur while the subject is breathing, before and after exposure to a drug or other challenges.