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Vascular reactivity study using a myograph

Myographs are used to determine the myogenic tone, evaluate the impact of treatment on Vascular Smooth Muscle Cells contractility and study endothelial function.

This application note includes:

  • An introduction about wire myography
  • The list of material required for small and large vessel dissection
  • Dissection and isolation tips
  • Tissue mounting protocol
  • A reminder about Normalization
  • Some considerations about Dose-response curves