Vascular reactivity study using tissue bath systems

The impact of different drugs on relaxation or contraction of the endothelium or vascular smooth muscles can be investigated using isolated tissue bath protocols.

This application note includes:

• An introduction about the crucial role of the endothelium
• A focus on recent studies where tissue baths were used to investigate cardiovascular diseases: Atherosclerosis, hypertension, heart failure, diabetes and metabolic syndrome
• A protocol explaining how to set an experiment to study rodents aorta rings on tissue bath