Taking advantage of new models and tools to rethink efficacy and Safety Research
During the 2023 Safety Pharmacology Society (SPS) Conference in Brussels, Dr. Dany Salvail (IPST, QC, Canada) explained how experienced pharmacologists rely on alternate models combined with sophisticated measurement techniques that go well beyond the ICH guidelines to help sponsors truly understand and quantify liabilities associated with their lead compounds early on.
Swine, the other tox species
During the 2023 Safety Pharmacology Society (SPS) Conference in Brussels, Dr. Donald Hodges (CBSET, MA, USA) outlined how proven translational characteristics and historical data are enabling the wider adoption of swine as an alternative to dogs and Non-Human Primates in the context of shortages and rising costs.
Use of the rat in cardiovascular screening assays
During the 2023 Safety Pharmacology Society (SPS) Conference in Brussels, Dr. Michael Stonerook (AmplifyBio, OH, USA) highlighted the benefits and limitations of the rat model for cardiovascular screening assays.
Accurately Phenotyping Arrhythmia in rodents
Finding arrhythmias in rodents can be tedious, thrilling, and controversial. During the 2023 Society of Toxicology (SOT) conference in Nashville, Dr. Alex Carll discussed rodent ECG morphology and physiologic vs. pathologic arrhythmias in mice and rats.
Mitigating transient arrhythmogenicity in pig following human cardiomyocyte transplantation
To achieve therapeutic cardiac regeneration, the University of Washington Medicine Heart Regeneration Program has been focusing on remuscularization with genuine cardiomyocytes derived from pluripotent stem-cells.
Home – Japan
At the forefront of preclinical research Physiological data monitoring We are delighted to announce a formal partnership between Orange Science and emka TECHNOLOGIES Japan to better serve the Japanese biomedical research community. As part of this partnership, Orange Science has become the exclusive distributor of emka TECHNOLOGIES preclinical instrumentation throughout Japan. Nisso No.18 Building 5F, […]
Orange Science partners with emka Japan
Orange Science partners with emka Japan We are delighted to announce a formal partnership between Orange Science and emka TECHNOLOGIES Japan to better serve the Japanese biomedical research community. As part of this partnership, Orange Science has become the exclusive distributor of emka TECHNOLOGIES preclinical instrumentation throughout Japan. Key personnel from emka’s Japanese subsidiary have […]
Vascular function study using a myograph
Myographs are used to determine the myogenic tone, evaluate the impact of treatment on Vascular Smooth Muscle Cells contractility and study endothelial function.
Funding Opportunities
Research Funding Directory emka TECHNOLOGIES is proud to offer a comprehensive hub of funding sources, to help support and further develop the preclinical research field. Please do not hesitate to reach out if you require any quotes, project proposals or literature reviews to help with upcoming grant submissions. Get an equipment project proposal for […]
Accurately Phenotyping Arrhythmia and Arrhythmogenicity in Preclinical Models
The Art of Phenotyping Cardiac Arrhythmias in Rodents Dr. Alex Carll studies the mechanisms by which inhaled toxins impair cardiac conduction and contraction, in both rodents and humans, with particular interest in the autonomic nervous system’s role. Dr. Alex Carll discussed the art of phenotyping cardiac arrhythmias in rodents during the 2023 Society of Toxicology […]
