press-release-Yael-Mamane
Le groupe emka TECHNOLOGIES/SCIREQ est fier d’accueillir Mme Yael Mamane au sein de son conseil d’administration. emka TECHNOLOGIES/SCIREQ group is proud to welcome Ms. Yael Mamane to its board of directors. Montréal, 30 Novembre, 2023 : Dr Yael Mamane est directrice principale du département de biologie cellulaire et des sciences translationnelles chez NuChem Sciences, un […]
Cardiomyopathy
Cardiomyopathy Cardiomyopathy is a group of diseases that affect the myocardium. The heart muscle becomes enlarged, thickened, or stiff, which can lead to problems with the heart’s ability to pump blood effectively, and can cause heart failure, cardiac fibrosis or arrhythmias. This condition can be caused by a variety of factors, including genetics (syndrome of […]
Taking advantage of new models and tools to rethink efficacy and Safety Research
During the 2023 Safety Pharmacology Society (SPS) Conference in Brussels, Dr. Dany Salvail (IPST, QC, Canada) explained how experienced pharmacologists rely on alternate models combined with sophisticated measurement techniques that go well beyond the ICH guidelines to help sponsors truly understand and quantify liabilities associated with their lead compounds early on.
Swine, the other tox species
During the 2023 Safety Pharmacology Society (SPS) Conference in Brussels, Dr. Donald Hodges (CBSET, MA, USA) outlined how proven translational characteristics and historical data are enabling the wider adoption of swine as an alternative to dogs and Non-Human Primates in the context of shortages and rising costs.
Use of the rat in cardiovascular screening assays
During the 2023 Safety Pharmacology Society (SPS) Conference in Brussels, Dr. Michael Stonerook (AmplifyBio, OH, USA) highlighted the benefits and limitations of the rat model for cardiovascular screening assays.
Accurately Phenotyping Arrhythmia in rodents
Finding arrhythmias in rodents can be tedious, thrilling, and controversial. During the 2023 Society of Toxicology (SOT) conference in Nashville, Dr. Alex Carll discussed rodent ECG morphology and physiologic vs. pathologic arrhythmias in mice and rats.
Mitigating transient arrhythmogenicity in pig following human cardiomyocyte transplantation
To achieve therapeutic cardiac regeneration, the University of Washington Medicine Heart Regeneration Program has been focusing on remuscularization with genuine cardiomyocytes derived from pluripotent stem-cells.
Home – Japan
At the forefront of preclinical research Physiological data monitoring We are delighted to announce a formal partnership between Orange Science and emka TECHNOLOGIES Japan to better serve the Japanese biomedical research community. As part of this partnership, Orange Science has become the exclusive distributor of emka TECHNOLOGIES preclinical instrumentation throughout Japan. Nisso No.18 Building 5F, […]
Orange Science partners with emka Japan
Orange Science partners with emka Japan We are delighted to announce a formal partnership between Orange Science and emka TECHNOLOGIES Japan to better serve the Japanese biomedical research community. As part of this partnership, Orange Science has become the exclusive distributor of emka TECHNOLOGIES preclinical instrumentation throughout Japan. Key personnel from emka’s Japanese subsidiary have […]
Autonomic dysfunction
Autonomic dysfunction The Autonomic Nervous System, comprising the Sympathetic Nervous System (SNS) and Parasympathetic Nervous System (PNS), regulates essential physiological functions such as heart rate and blood pressure. These systems help control blood pressure through the baroreflex (or baroreceptor reflex) mechanism(1). The baroreflex is a homeostatic physiological mechanism that regulates blood pressure at constant levels. […]
