Using Non-Invasive Impedance to Assess Respiratory Function
Using Non-Invasive Impedance to Assess Respiratory Function During the 2024 Society of Toxicology (SOT) Conference in Salt Lake City, Ken Kearney (Charles River Laboratories) shared the results of a study, evaluating the ability of our jacketed external telemetry system to capture ECG and respiratory data simultaneously, from ECG leads. He also explored the process of […]
E-cigarettes induce Cardiac Arrhythmia and Conduction Defects In Mice
e-cigarettes induce cardiac arrhythmia and conduction defects in mice This document provides a summary of the study by Dr. Carll et al. at the University of Louisville published in Nature Communications: E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice. Carl, A., et al. (2022). Nature Communications, 13(1):6088. doi: 10.1038/s41467-022-33203-1. It […]
Respiratory applications
Control of breathing
Control of Breathing Respiration functions through a complex network of neural controls and feedback mechanisms as the body constantly adjusts its breathing rate and tidal volume to meet respiratory metabolic demands. Several diseases and conditions disrupt the neurological and muscular signals, compromising the body’s ability to breathe normally. Neurologic and muscular disorders like Duchenne muscular […]
Pulmonary hypertension
Pulmonary Hypertension Pulmonary hypertension (PH) is a condition characterized by elevated blood pressure in the arteries of the lungs, often leading to heart failure if left untreated. Preclinical research on PH involves various approaches to understand its pathophysiology and develop potential treatments. Animal models, particularly rodents and larger mammals, are commonly used to mimic PH […]
