Swine, the other tox species

Swine the other tox species

Swine, the “other large animal” tox study During the 2023 Safety Pharmacology Society (SPS) Conference in Brussels, scientists from leading preclinical contract organizations (CROs) discussed how traditional IND-enabling studies involving primates and dogs can be complemented (and sometimes even replaced) by alternative models such as mice, rats, rabbits and pigs. Dr. Donald Hodges (CBSET, MA, […]

Toxicology

Toxicology

Preclinical Toxicology studies Preclinical toxicology investigates the adverse effects of test articles (e.g. drugs, toxins, and other agents) on various model systems to evaluate clinical risk. Preclinical toxicology integrates many disciplines to investigate a compound’s safety profile, including genotoxicity, mutagenicity, repeat-dose cardiotoxicity, neurotoxicity, and general toxicology. In the United States, toxicology studies are regulated by […]

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