Telemetry represents the only technique currently available for data collection from unrestrained, freely moving mice.
Through the use of telemetry, it is possible to gather data continuously, for longer periods of time, from animals residing in their own familiar environment, thus minimizing stress to the animals and consequent experimental artifacts. Furthermore, in vivo studies from conscious, unanesthetized, instrumented animals are recommended by the FDA for ICH S7A studies.
The easyTEL system can simultaneously collect signals from implants, analog signals, biopotential electrodes and/or strain gauge transducers. This is particularly useful for neurorespiratory or cardiorespiratory applications. For example, pleural pressure from an implant and respiratory flow from a head-out plethysmograph can be simultaneously recorded, for precise resistance & compliance measurement.
Wireless implanted telemetry provides the unique ability to discover and review long-term physiological trends, as well as rare or isolated physiological events (arrhythmias, seizures, etc.).
Our implanted telemetry permits continuous data recording up to 90 days, with up to 64 single-housed mice per system.
Cardiotoxicity studies can also benefit from telemetry. Telemetry can be used in nanotoxicology to assess physiology in animals exposed to nanoparticles. As Hoay Yan Cheah says, “Telemetry provides an unlimited capacity for continuous data acquisition over days, weeks or even months“.
Implants are priced for single use, eliminating the need for refurbishment and associated logistics, costs, and delays (implants can be re-implanted as long as battery lasts).
A single device monitors ambient pressure, handles data and power, and connects to the computer.
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