Arrhythmia
Arrhythmia Cardiac arrhythmias are abnormalities in the generation or conduction of electrical impulses within the heart. They can manifest as bradycardia, tachycardia, ectopic beats, conduction blocks, or more severe events such as ventricular tachycardia, ventricular fibrillation, and Torsade de Pointes. In preclinical research, arrhythmia assessment plays an essential role in cardiovascular safety pharmacology, disease modeling, and […]
Behavioral studies
Behavioral studies The study of behavior is a major element of preclinical neuroscience research. Behavioral tests are used to characterize changes in brain function that may be produced by disease, neural injury, genetic modification, drug abuse and addiction, or exposure to various agents and treatments. Our close working relashionship with Noldus Information Technology, along with […]
Medical Countermeasures Research for Infectious Disease & CBRN threats
Medical Countermeasures Research for Infectious Disease & CBRN threats As defined by the FDA, Medical Countermeasures (MCM) are critical tools for protecting against infectious diseases and chemical, biological, radiological, or nuclear (CBRN) threats. MCM research requires specialized approaches to understand both the physiological effects of a threat and the efficacy of potential countermeasures. Preclinical evaluation […]
Toxicology
Preclinical Toxicology studies Preclinical toxicology investigates the adverse effects of test articles (e.g. drugs, toxins, and other agents) on various model systems to evaluate clinical risk. Preclinical toxicology integrates many disciplines to investigate a compound’s safety profile, including genotoxicity, mutagenicity, repeat-dose cardiotoxicity, neurotoxicity, and general toxicology. In the United States, toxicology studies are regulated by […]
Safety Pharmacology
Safety Pharmacology Safety pharmacology investigates potential undesirable effects of drugs on physiological functions, to predict safety before bringing to market. emka TECHNOLOGIES provides complete solutions to meet your GLP or non-GLP Safety Pharmacology needs. Our solutions allow for efficient data collection and analysis, in-line with ICH requirements, spanning in-vivo and ex-vivo applications. The core battery […]
Traumatic Brain Injury
Traumatic Brain Injury Traumatic Brain Injury (TBI) is defined as a damage to the brain resulting from an external mechanical force. TBI is a complex disease process (Masel BE & DeWitt DS, 2010) and several studies have demonstrated that long-term functional and structural changes take place up to one year after TBI (Smith DH et […]
emkapack large animals- Techniques and Measurement
Techniques & Measurements This page lists techniques and measurements employed bythe emkaPACK5 system for large animals, and used in the areaof measuring cardiovascular and respiratoryoutcomes. Wireless non-invasive telemetry telemetry | Electrocardiogram | Blood Pressure | Respiratory Inductive Plethysmography | Acceleration Wireless non-invasive telemetry Physiological measurements are captured non-invasively by the transmitter housed in a jacket. […]
emkapack – Specifications
Specifications emkaPACK5 system consists of transmitters, receivers, an ethernet switch and an acquisition computer. Detailed specifications ofthe emkaPACK5 system capabilities are provided in the tables below. For a customized quotation that meets your research needs, please contact emka TECHNOLOGIES Customer Service.
emkaPACK- System Configuration & Extensions
System Configuration & Extensions Basic System | Implanted Telemetry Extension | Snapshot option Basic System An external transmitter is worn into a jacket and provides physiological signals from each animal. Various sensors are plugged to the transmitter: External electrodes to record up to 9-lead ECG 1 or 2 belts to record lung volume by Respiratory […]
EEG+ analysis module
EEG+ analysis module EEG+ is an in-depth neurological analysis module that is part of the ecgAUTO software. It generates FFT* power spectra and performs automated seizure detection and sleep scoring from EEG**, with optional synchronized video. Additional analysis options include EMG***, diaphragmatic EMG, temperature, and activity. Customizable parameters and protocols, interactive dashboards, batch analysis, comprehensive […]
