ecgAVG module
ecgAVG module ecgAVG is a software module available within IOX2 software, or as a standalone module, to acquire and analyze average ECG beats. This module is particularly recommended and well suited to analyze rodents ECG recordings acquired with the ecgTUNNEL device. Request information Request a web demo Designed for snapshot ECG analysis Snapshot Electrocardiogram recordings […]
Cardiotoxicity
Cardiotoxicity studies Cardiotoxicity refers to damage or dysfunction of the heart caused by exposure to drugs, environmental pollutants, or other toxic agents. It is a critical concern in drug development and environmental health, often leading to heart failure, arrhythmias, and electrophysiological abnormalities. Functional cardiovascular outcomes such as electrocardiograms (ECGs), blood pressure, and other hemodynamic endpoints can offer powerful insights […]
Vascular Biology
Vascular Biology Vascular biology implies understanding mechanisms involved in vascular tone, hemostasis, thrombosis and pathobiology of ischemic syndrome, remodeling, and plaque formation. It involves functional assessment of endothelial and smooth muscle cells in the vascular system. The major regulator of vascular homeostasis is the endothelium, which is a thin layer of cells that line the […]
Heart failure & cardiac model development
Heart failure & cardiac model development Heart failure occurs when the heart cannot pump enough blood to meet the body’s demands. This decline in contractile function is caused by a variety of conditions but mainly following myocardial infarction, when blood flow to the heart is reduced. ECG, Blood pressure and Blood flow investigation The investigation […]
Arrhythmia
Arrhythmia Arrhythmia is a condition where the heart beats with an irregular rhythm, due to a change in the electrical impulses to the heart. These changes affect the heart’s ability to pump blood effectively, leading to other organs (i.e. lungs) becoming damaged. Arrhythmia, also known as Heart arrhythmia, dysrhythmia, or irregular heartbeat, can be categorized […]
Behavioral studies
Behavioral studies The study of behavior is a major element of preclinical neuroscience research. Behavioral tests are used to characterize changes in brain function that may be produced by disease, neural injury, genetic modification, drug abuse and addiction, or exposure to various agents and treatments. Our close working relashionship with Noldus Information Technology, along with […]
Medical Countermeasures Research for Infectious Disease & CBRN threats
Medical Countermeasures Research for Infectious Disease & CBRN threats As it is related to infectious disease and chemical, biological, radiological, or nuclear (CBRN) threats, Medical Countermeasures (MCM) research* and development is unique and requires specific solutions throughout the process of data capture and analysis. When studying CBRN threats, it is important to understand the effect […]
Toxicology
Preclinical Toxicology studies Preclinical toxicology investigates the adverse effects of test articles (e.g. drugs, toxins, and other agents) on various model systems to evaluate clinical risk. Preclinical toxicology integrates many disciplines to investigate a compound’s safety profile, including genotoxicity, mutagenicity, repeat-dose cardiotoxicity, neurotoxicity, and general toxicology. In the United States, toxicology studies are regulated by […]
Safety Pharmacology
Safety Pharmacology Safety pharmacology investigates potential undesirable effects of drugs on physiological functions, to predict safety before bringing to market. emka TECHNOLOGIES provides complete solutions to meet your GLP or non-GLP Safety Pharmacology needs. Our solutions allow for efficient data collection and analysis, in-line with ICH requirements, spanning in-vivo and ex-vivo applications. The core battery […]
Traumatic Brain Injury
Traumatic Brain Injury Traumatic Brain Injury (TBI) is defined as a damage to the brain resulting from an external mechanical force. TBI is a complex disease process (Masel BE & DeWitt DS, 2010) and several studies have demonstrated that long-term functional and structural changes take place up to one year after TBI (Smith DH et […]
