Arrhythmia detection: Part 1 – The electrical system of the heart
Detecting arrhythmia The electrical system of the heart This is the first in a series of articles intended to assist in identifying and detecting arrhythmias in the heart using emka TECHNOLOGIES ecgAUTO software. We will begin this series by introducing – in very general terms – the electrical system of the heart, followed by a […]
Arrhythmia detection: Part 2 – Identifying premature ventricular contractions with ecgAUTO
Detecting arrhythmia Identifying premature ventricular contractions with ecgAUTO This document is a guide to help identify and quantify Premature Ventricular Contractions (PVC’s) in ecgAUTO. These guidelines will allow for consistent data interpretation for this type of arrhythmia. To learn more, read also: Detecting arrhythmia : Part 1 – The electrical system of the heart
Isolated heart techniques
Isolated heart techniques Isolating the heart is an ex vivo technique used to investigate small mammalians cardiac function, in health and disease, or following drug challenges. Nowadays, both Langendorff heart and working heart techniques are commonly used. But what is the difference between both techniques? This guide includes: A short video introducing both methods Diagrams […]
Heart Rate Variability: Part 1 – Frequency domain analysis
Frequency domain analysis of Heart Rate Variability in ecgAUTO This is the first document of our serie of technical notes discussing Heart Rate Variability (HRV) analysis. It introduces the Frequency Domain analysis, which is an effective method to analyze heart rate dynamics. In this document, you will learn how ecgAUTO software uses your data to […]
Heart Rate Variability: Part 2 – Configuring FFT Sampling parameters
Configuring FFT Sampling parameters in HRV analysis This document discusses the proper usage of the Fast Fourier Transform (FFT) Analysis Parameters, using the Heart Rate Variability (HRV) Analysis Module in ecgAUTO. The topics of resampling, data exclusion along with Epochs are covered in this document. Read also: Heart Rate Variability: Part 1 – Frequency domain […]
Heart Rate Variability: Part 3 – FFT windows
Understanding FFT Windows in ecgAUTO software The Heart Rate Variability (HRV) module in ecgAUTO performs advanced frequency domain analysis of cardiovascular electrophysiology signals using the Fast Fourier Transform (FFT). This approach permits detailed analysis of heart rate changes with great sensitivity and helps scientists visualise comprehensive datasets in the time and frequency domains. FFT analysis […]
Vascular reactivity using tissue bath systems
Guidelines for external ECG recording on laboratory animals This document provides an overview of ecgAUTO’s analysis methodologies and capabilities for preclinical cardiovascular research, including ECG Interval and Arrhythmia analysis. It includes: – ECG interpretation and physiological description – ecgAUTO standard workflow – Applications of automated ECG analysis (Abnormal event detection, variability analysis, visualization of large […]
Guidelines for external ECG recording on laboratory animals.
Guidelines for external ECG recording on laboratory animals This document provides an overview of ecgAUTO’s analysis methodologies and capabilities for preclinical cardiovascular research, including ECG Interval and Arrhythmia analysis. It includes: ECG interpretation and physiological description ecgAUTO standard workflow Applications of automated ECG analysis (Abnormal event detection, variability analysis, visualization of large dataset)
Cardiotoxicity
Cardiotoxicity studies Cardiotoxicity can be described as dysfunction of the heart stemming from exposure to drugs, pollutants, or other toxins. The irreversible cardiac dysfunction and development of heart failure is characterized by electrophysiological, morphological, and biochemical alterations. Cardiotoxicity is often associated with a decline in left ventricular ejection fraction (LVEF) and autonomic disbalance. Drug-induced cardiotoxicity […]
Vascular Biology
Vascular Biology Vascular biology implies understanding mechanisms involved in vascular tone, hemostasis, thrombosis and pathobiology of ischemic syndrome, remodeling, and plaque formation. It involves functional assessment of endothelial and smooth muscle cells in the vascular system. The major regulator of vascular homeostasis is the endothelium, which is a thin layer of cells that line the […]