Implants for rats

easyTEL+ is a fully implantable digital system, that transmits physiological data from conscious freely moving laboratory animals.

Intended for use in preclinical research (primarily toxicology, phar­macology and safety pharmacology studies) and biodefense, the easyTEL+ implants are ideal for rodents > 200g such as rats.

Various models offer the ability to continuously record Biopotential (ECG*, EEG*, EMG*, EOG*), Blood pressure (Arterial and/or Left Ventricular Pressure), Respiratory rate**, Temperature and Acceleration.

*Electrocardiogram (ECG), electroencephalogram (EEG), electromyogram (EMG),
electrooculogram (EOG)
**Derived from pleural or blood pressure or diaphragmatic EMG

Basic digital system

A typical setup includes implants, receivers, an Ethernet switch and an acquisition computer.

A single ethernet cable provides power and data transmission between the receiver and PC. Cameras can be added for synchronized video recording.

Head-mounted system for rats can be added to the same setup.

 

Analog system

Analog implants are also available for rodents (see our models in the Technical specification section). The analog technique is older and does not allow subject group-housing.

However, it allows to collect and combine synchronized signals from implants and any other source (analog signal, biopotential electrodes, strain gauge transducers) with easyMATRIX3.
This is particularly useful for cardio or neurorespiratory applications. For instance, pleural pressure from an implant and respiratory flow from a head-out plethysmography can be simultaneously recorded, for precise resistance & compliance measurement.

 

A typical analog setup includes:

  • Implants: to capture physiological measurements
  • Receivers: For rats, one receiver per implant is placed below the cage, to receive physiological signals wirelessly transmitted
  • A computer: equipped with IOX2 acquisition software
  • An easyMATRIX3: Linked to the computer, it connects up to 16 telemetry receivers and 8 analog inputs (Up to 4 easyMATRIX3 connect to a single computer).

As easyMATRIX3 contains its own ambient pressure transducer, no external ambient pressure reference monitor is required.

Up to 8 analog signals can be simultaneously acquired and synchronized with signals coming from the implant. Additional transducers are therefore added to the basic system:

  • Biopotential electrodes, for ECG, EEG, or EMG recording (signal is amplified by easyMATRIX3)
  • Strain gauge transducers (differential pressure or blood pressure transducers), powered and amplified by easyMATRIX3
  • Analog signals already amplified (connected through Lemo-BNC adapters)

 

Combined behavior tracking system

Adding an easySYNC device to the basic system allows to track and analyze the behavior, movement, and activity of an animal in Noldus EthoVision software while synchronizing physiological data from easyTEL+ telemetry system. Learn more.

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